Hyperosmotic modulation of the cytosolic calcium concentration in a rat osteoblast-like cell line.
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چکیده
منابع مشابه
Effects of Antiproliferative Protein (APP) on Modulation of Cytosolic Protein Phosphorylation of Prostatic Carcinoma Cell Line LNCaP
Antiproliferative protein (APP) isolated from conditioned media of two androgen-independent prostatic carcinoma cell lines, PC3 and Du-145 was shown to inhibit selectively cell proliferation of androgen-dependent prostate cancer cell line LNCaP in a dose dependent manner. This protein was further purified with HPLC using hydrophobic interaction column (phenyl 5PW) and was used to study the modu...
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The effects of protein kinase C stimulation on free cytosolic Ca2+ [( Ca2+]i) were studied in Fura 2-loaded UMR-106 cells. Stimulation of the protein kinase C with the tumor-promoting phorbol esters 12-O-tetradecanoylphorbol 13-acetate (TPA) and phorbol 12,13-diacetate or 1-oleoyl-2-acetylglycerol was followed by an increase in [Ca2+]i. The protein kinase C-induced increase in [Ca2+]i has a lag...
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چکیده ندارد.
15 صفحه اولParathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. cAMP-dependent and cAMP-independent calcium channels.
Changes in free cytosolic calcium were measured in UMR-106 cells in response to parathyroid hormone (PTH) stimulation. Bovine PTH-(1-34) induced an increase in [Ca2+]i with the contour of the rise in [Ca2+]i occurring in three successive phases: a rapid increase in [Ca2+]i occurring within seconds, rapid decrement in [Ca2+]i to near-resting levels within 1 min, and slow increment in [Ca2+]i. Ph...
متن کاملAn Elevation in the Concentration of Free Cytosolic Calcium
In granulocytes harvested from human blood, an elevation of the cytosolic concentration of Ca” ions is by itself insufficient to activate the cell’s respiratory burst. We report herein that, when granulocytes are “primed” by a 90-min preincubation with the recombinant human hemopoietic growth factor granulocytemacrophage colony-stimulating factor (GM-CSF,,,), elevation of the concentration of c...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1995
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1995.sp020793